2006, Vol.13, pp.29-36
A turbidostat is a continuous bioreactor in which the
biomass concentration level is controlled by regulation of the
dilution rate. In this paper, the behaviour of an aerobic
Saccharomyces Cerevisiae culture in a turbidostat regulated
by a PI feedback controller is discussed. In particular, it will
be shown how the cybernetic model of Jones & Kompala [1], based on the
competition among oxidative and fermentative metabolic pathways
and capable of describing some dynamic features of the system, can
predict the presence of chaotic regimes in a specific range of
operating parameters of the controller. The transition to chaos is
determined by period doubling and intermittency according to
Feigenbaum scenario, but the shift among different metabolic routes
causes some unusual behaviours of the periodic windows.
Key words:
turbidostat, chaotic oscillations, yeasts, cybernetic model
Full text: Acrobat PDF (548KB)